Gnosis - Advanced biotech

Gnosis is a biotechnology company specialised in the manufacturing and sales of fermentation raw materials and natural finished products used in the pharmaceutical, nutraceutical, cosmetic, veterinary and agricultural industries.

With an international manufacturing network dedicated to high-quality and proprietary products and a successful integration between R&D and GMP-approved manufacturing facilities, Gnosis constantly works to develop and introduce innovative and exclusive products to increase consumer's health and wellbeing.

The Gnosis Group includes a European manufacturing network made up of three operating divisions and three commercial operations located in Italy, the US and China.

The corporate headquarters in Desio (Milan, Italy) is organised in a R&D centre, which is equipped with modern research laboratories, and global commercial operations driving strategic initiatives across Europe and the rest of the world. The American branch office (Doylestown, US) is responsible for providing client-oriented services and to develop Gnosis marketing plans in the US and Canada. The Asia-Pacific branch office (Shanghai, China) works to strengthen and consolidate Gnosis' presence within the developing markets creating business relationships and performing crossover support among geographic areas.

Manufacturing includes two pharmaceutical cGMP approved plants, our Sant'Antonino Operations known as Gnosis Bioresearch SA (Bellinzona, Switzerland) and our Pisticci Operations known as Gnosis Bioresearch Srl (Matera, Italy). Gnosis has integrated the value chain from the development to the commercialisation of its products by combining outstanding R&D with advanced manufacturing capabilities.

While manufacturing and developing innovative products and services is the cornerstone of our business, we at Gnosis are equally committed to quality, safety, health and the environment. In fact all of Gnosis sites adhere to strict global quality standards. This is backed by first-class, worldwide quality control and quality assurance teams.

Advanced nutrition

Gnosis develops the "Advanced Nutrition concept" exploring the effects of nutrients on human health, with the growing awareness that customers, consumers and also professional healthcare providers are becoming more aware of the benefit of nutrition as a way to improve wellness and wellbeing. Gnosis Advanced Nutrition offers customers an extensive range of differentiated solutions improving and boosting human head-to-toe health condition.

The evolution of knowledge in the field of nutrition has highlighted the biological importance of several compounds involved in the control of gene expression. This epigenetic components may be crucial to sustain key biological processes and to counteract the onset of age-related diseases.

Branded Ingredients:

  • Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate and is structurally analogous to the reduced and active form of folic acid. It provides greater stability, higher water solubility and multiple ingredients formulation flexibility compared to 5-methyltetrahydrofolate calcium salt.
  • VitaMK7® is the active isomer of natural Vitamin K2 with the highest bioavailability and longest half-life in the blood. K2&Olive™ combines nutritional beneficial properties of extra virgin olive oil and benefits of Menaquinone-7.
  • Biootic™ is a probiotic yeast (Saccharomyces boulardii) acting as a temporary flora to protect intestinal tract and good germs in the intestine.
  • Adonat® is the commercially stable form of S-Adenosyl-L-methionine (SAMe) and it has been shown to have mood enhancing, hepatoprotective and pro-joint activities. Adomet® is produced from a selected proprietary highly productive yeast using fermentation technologies which generate a superior quality of the ingredient.
  • Adomix®, is the SAMe stabilized powder for fast drug absorption and extensive formulation possibilities in capsule dosage.
    Adogran®, is a formulated bulk powder consisting of coated granules containing SAMe.
  • SamEspresso® is the mouth soluble granulate with improved stability and fast SAMe release.
  • SupereSSe® is the dried yeast (Saccharomyces cerevisiae) with a high content of the enzymatically active active form (S,S) Adenosyl-methionine.
  • Adomet Tablets® Conventional enteric-coated tablets in different dosages and combinations for direct release of the ingredient in the intestine, good absorption and tolerability.
  • Soloesse®, are All Natural Tables offering the absence of synthetic derivatives for consumers, asking for all-natural ingredients.
  • Adonat™ a newly stabilized bulk powder of SAMe in the form of phytate, where the salt has a synergic action with SAMe
  • SAMe Drink® is a mouth-soluble granulate, alternative for people who cannot swallow or who dislike swallow coated tablets.
  • Mythocondro® is the first Non-Animal Chondroitin Sulfate produced by a patented fermentation-based manufacturing process.
  • Emothion™ is S-Acetyl Glutathione, an alternative form of the reduced GSH. Several studies have shown that this precursor of GSH is well-absorbed and more stable throughout the digestive tract than the L-glutathione reduced and has a positive effect on many oxidative stress biomarkers.
  • TH Queen® are GSH gums with rapid release of glutathione and easy absorption through the mouth.
    Phosphocomplex™ is obtained from the complexation of Silybin with phospholipids. Silybin is the primary active flavonolignan in Silymarin extract (milk thistle plant) used so far as hepatoprotectants

BIOPHARMA We are a leading developer, manufacturer and trusted supplier of difficult to manufacture fermented and semisynthetic APIs (Active Pharmaceutical Ingredients) derived from yeasts and bacteria. Active pharmaceutical ingredients (APIs) can be produced by these microorganisms using applied biotechnology. Gnosis is able to manufacture several APIs in large scale through biofermentation and to modify the structure of natural metabolites obtained by synthesis and semisynthesis.

Products and Services

Contact Details

Gnosis S.p.A.
Via Lavoratori Autobianchi, 1
20832 Desio (MB)
Tel: +39.0362.48.84.1
Fax: +39.0362.48.84.40
Email: [email protected]

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