The vaginal balance is fragile and can be disrupted in response to internal and external stresses such as hormonal variations, drug exposure like antibiotics treatment, environmental factors contraception, and even menstruation. 

As many as 75% of women will know a vaginal infection in their lifetime and more than 372 million women will be affected by recurrent vulvovaginal candidiasis over their lifetime. Vaginal dysbiosis is an extremely disabling condition, leading to a range of symptoms having potentially important consequences on women’s life (health, sexuality, quality of life, self-confidence) a high rates of resistance and recurrence after the pharmaceutical treatment with antimicrobial agents that remain the main strategy for the treatment, getting a sense of frustration and anxiety. 

Preventing or restoring the imbalance of the vaginal microbiota have always represented a clear need of the market and probiotic treatments have been considered important to protect and avoid the disruption in the vaginal microbiome, helping to prevent those infections and the discomfort (dryness, burning, itching, pain) that occurs afterward.

However, the awareness of the yeast probiotic benefits and the main differences with bacterial probiotics are not well known. It will help to regulate and balance the intimate microbiome that often is weakened during infections period.

Quatreflora™, the yeast solution for vaginal health

Quatreflora™, the brand of a clinically proven yeast solution for vaginal health, is obtained from the patented yeast Saccharomyces cerevisiae CNCM I-3856, proprietary of Gnosis by Lesaffre, and is an ally for intimate wellbeing. Quatreflora® contributes to restoring the normal vaginal flora with several mechanisms also during antibiotic treatments, improving its functionality and physiological state and limiting the probability of new external aggressions, especially by yeasts such as Candida albicans


The efficacy and the mechanism of action have been clinically tested, with proven migration of the yeast Saccharomyces cerevisiae CNCM I-3856 -Quatreflora™- from the rectum to the vagina that has never been described, effective after just 4 weeks of oral supplementation. 

Infographic tool to settle the differences and features of Quatreflora™

The main differences between Quatreflora™ and the probiotic bacteria have been easily described in an infographic, reporting all the clinical references and studies supporting the ingredient and helping woman health. For more information contact us and visit