NIZO Food Research - Health claim building

NIZO's research centre provides scientific and clinical expertise that helps companies worldwide prove their products' health claims. From investigating the mechanism of an action to substantiating the health benefits of a company's food ingredients or products, NIZO combines outstanding scientific knowledge with innovative trial execution and microbiome expertise.

NIZO uses 'human challenge models' to make decisions on the most promising of ingredients, to determine the best way forward in the development of a product or to demonstrate health benefits.

Human challenge studies: allowing data-driven decisions

Human challenge models are a unique approach used to induce a physiological response in healthy subjects and to investigate how an active ingredient modulates this response. NIZO applies human challenge models to the areas of metabolic health, immune response, infection resistance, gut barrier, and skin and physical health.

The benefits of human challenge studies include:

  • ??strategic benefits for alignment with European Food Safety Authority requirements for scientific substantiation, such as gut and immune response health advantages
  • ??financial benefits, in that fewer subjects shorter timelines are needed compared with population studies that use random exposure to stressors
  • ??scientific benefits, including reproducible outcomes, and high correlation between clinical outcome parameters, subject symptom scores and biomarkers of infection
  • ??organisational benefits, like high subject compliance from following study guidelines and low subject drop-out rates.

To find out more about NIZO's clinical and microbiome research, please visit stand 8E23 at Hi Europe in November.

Products and Services

Contact Details

NIZO food research BV
Kernhemseweg 2
6718 BA Ede
Tel: +31 (0) 318 65 95 11
Fax: +31 (0) 318 65 04 00
Email: [email protected]

NIZO areas of expertise.
Delicious smoothie with extra protein, from plant protein fibres developed by NIZO.
Tasty coconut drink developed from coconut residue.
Intellicap, non-invasive sampling of the small intestine.
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